Recent Advances

Author- Dr. Mohammad Shamim, MD Overview of Recent Advances in The Treatment of AIDS The field of AIDS treatment has seen significant advancements, particularly in improving adherence to therapy, enhancing immune response, and exploring potential cures. These advancements are categorized into long-acting antiretroviral treatments, gene-editing and immunotherapy, novel cure strategies, and new potential treatments. Long-Acting […]

Author- Dr. Md. Shamim, MD Overview Recent advances in the treatment of type 2 diabetes mellitus (T2DM) have focused on enhancing glucose control, reducing cardiovascular risk, and improving patient outcomes. Here are some key developments. New Medications SGLT2 Inhibitors Mechanism of Action: Sodium-glucose co-transporter 2 (SGLT2) inhibitors work by preventing glucose reabsorption in the kidneys,

Author- Dr. Md. Shamim, MD Overview Heart failure, a chronic condition where the heart is unable to pump blood efficiently, has seen significant advances in treatment over recent years. These advances span from pharmacological innovations to mechanical devices and lifestyle interventions, offering new hope to patients worldwide. Pharmacological Innovations in the Treatment of Heart Failure

Author- Dr. Md. Shamim, MD Overview Hypertension remains a critical concern in global health, necessitating continuous advancements in its management. This detailed exploration delves into the latest innovations in pharmacological treatments, non-pharmacological interventions, personalized medicine, and digital health technologies to provide a comprehensive understanding of recent progress in hypertension treatment. Pharmacological Advances in the Treatment

Author- Dr. Md. Shamim, MD Overview Statin is the most effective drugs for lowering blood cholesterol levels. Clinical trials have shown that they prevent coronary artery disease and reduce mortality. Hypercholesterolemia causes development of atherosclerosis, which is a major contributary factor of coronary artery disease (CAD). Coronary Artery disease (CAD) is a leading cause of

Author- Dr. Md. Shamim, MD. Introduction: mTOR inhibitors are a class of drugs for coronary artery disease that specifically target the mTOR pathway. mTOR stands for mammalian target for Rapamycin or mechanistic target of Rapamycin. The mTOR pathway is an important regulator of cell growth, proliferation, and metabolism. It is involved in various cellular processes,

Author- Dr. Md. Shamim, MD Introduction Seizure is a transient occurrence of signs or symptoms due to abnormal excessive or synchron0us neural activity in the brain. Epilepsy is a recurrent seizure due to chronic, underlying process. Convulsion is a condition in which muscles contracts and relax quickly and causes uncontrollable shaking of the body. The

Author- Dr. Md. Shamim, MD. Introduction: Gestational Diabetes Mellitus is an abnormal glucose tolerance in pregnancy. It is due to an exaggeration of the pregnancy induced physiological changes in carbohydrate metabolism. At least 50% of women with GDM are diagnosed with overt diabetes at some point in their lifetime. During pregnancy principal concern about gestational

Author- Dr. Md. Shamim, MD. Introduction of Parkinson’s disease : Parkinson’s disease (PD) is a major neurodegenerative disease characterized by: – TRH Resting Tremor (Involuntary trembling when a limb is at rest). Rigidity Hypokinesia (Slowness of movement). Pathogenesis of Parkinson’s disease : Basal ganglia: Striatum Caudate Putamen Substantia nigra Globus pallidus Subthalamus This disease results

Author- Dr. Md. Shamim, MD. Introduction: Alzheimer’s disease is a major neurological disorder characterized by chronic and progressive dementia. Other mental abnormalities such as language abnormality, difficulty in calculation, unable to take judgement etc. are also associated with Alzheimer’s disease. It is a most common cause of dementia. Pathogenesis: Destruction of cholinergic neurons: Cortex Limbic